- CAS
- Purity
- 16452-01-0
- 99%
Chinese factory supply 3-METHOXY-4-METHYLANILINE 16452-01-0 in stock with high standard
- Molecular Formula: C8H11NO
- Molecular Weight: 137.181
- Appearance/Colour: Brown chunky solid
- Vapor Pressure: 0.021mmHg at 25°C
- Melting Point: 56-60 °C
- Refractive Index: 1.549
- Boiling Point: 251 °C at 760mmHg
- PKA: 4.61±0.10(Predicted)
- Flash Point: 109.6 °C
- PSA： 35.25000
- Density: 1.039 g/cm3
- LogP: 2.16700
3-METHOXY-4-METHYLANILINE(Cas 16452-01-0) Usage
|
Air & Water Reactions |
Sensitive to prolonged exposure to air. Insoluble in water. |
|
Reactivity Profile |
3-METHOXY-4-METHYLANILINE neutralizes acids in weakly exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Reacts with oxidizing agents . |
|
Fire Hazard |
3-METHOXY-4-METHYLANILINE is probably combustible. |
InChI:InChI=1/C8H11NO/c1-6-3-4-7(9)5-8(6)10-2/h3-5H,9H2,1-2H3
16452-01-0 Relevant articles
Preparation method of 6-tert-butyl-3 ', 3', 3-trimethyl pyran [3, 2-a] carbazole
-
Paragraph 0009-0010; 0027-0028, (2020/11/05)
The invention provides a preparation met...
Development of 2-thioxoquinazoline-4-one derivatives as dual and selective inhibitors of dynamin-related protein 1 (Drp1) and puromycin-sensitive aminopeptidase (PSA)
Numadate, Akiyoshi,Mita, Yusuke,Matsumoto, Yotaro,Fujii, Shinya,Hashimoto, Yuichi
, p. 979 - 988 (2015/02/19)
An established inhibitor ot dynamin-rela...
Efficient construction of pyrano [3, 2-a]carbazoles: Application to a biomimetic total synthesis of cyclized monoterpenoid pyrano [3, 2-a]carbazole Alkaloids
Hesse, Ronny,Gruner, Konstanze K.,Kataeva, Olga,Schmidt, Arndt W.,Kn?lker, Hans-Joachim
supporting information, p. 14098 - 14111 (2013/11/06)
We have developed a highly efficient rou...
Iron-mediated total synthesis of 2,7-dioxygenated carbazole alkaloids
Krahl, Micha P.,Kataeva, Olga,Schmidt, Arndt W.,Knoelker, Hans-Joachim
, p. 59 - 64 (2013/02/22)
We describe the efficient iron-mediated ...
16452-01-0 Process route
-
-
13120-77-9
2-methyl-5-nitroanisole
-
-
16452-01-0
ortho-cresidine
Conditions
| Conditions | Yield |
|---|---|
|
With
iron; acetic acid;
at 45 ℃;
for 3.5h;
Inert atmosphere;
|
100%
|
|
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
for 10h;
under 3750.38 Torr;
|
99%
|
|
With
hydrogen;
palladium on activated carbon;
In
ethanol; water;
for 3h;
under 2585.81 Torr;
|
98%
|
|
With
5%-palladium/activated carbon; hydrogen;
In
tetrahydrofuran;
for 5h;
|
98%
|
|
With
hydrogen;
palladium 10% on activated carbon;
In
ethanol;
at 18 - 22 ℃;
for 6.5h;
under 760.051 Torr;
|
97%
|
|
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 20 ℃;
|
97%
|
|
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 20 ℃;
for 5.5h;
under 750.075 Torr;
|
95%
|
|
With
ethanol; nickel;
Hydrogenation;
|
|
|
With
sodium disulfide;
|
|
|
With
hydrogenchloride; ethanol; tin(ll) chloride;
|
|
|
With
iron; acetic acid;
at 100 ℃;
for 2h;
|
|
|
With
hydrogen;
Ni-Raney;
In
methanol;
at 20 ℃;
under 760.051 Torr;
|
|
|
With
palladium 10% on activated carbon; hydrogen;
In
ethyl acetate;
for 5h;
|
|
|
With
hydrogen;
Ni-Raney;
In
methanol;
at 20 ℃;
under 760.051 Torr;
|
|
|
With
hydrogen;
In
methanol;
at 20 ℃;
under 760.051 Torr;
|
1.86 g
|
-
-
tin(II)chloride dihydrate
-
-
13120-77-9
2-methyl-5-nitroanisole
-
-
16452-01-0
ortho-cresidine
Conditions
| Conditions | Yield |
|---|---|
|
In
ethanol; ethyl acetate;
|
86%
|
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-
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-
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-
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-
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-
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