- CAS
- Purity
- 7377-26-6
- 99%
Location：Home > Pharmaceutical
Manufacturer supply top purity Methyl 4-chlorocarbonylbenzoate 7377-26-6 with GMP standards
- Molecular Formula: C9H7ClO3
- Molecular Weight: 198.606
- Appearance/Colour: slight yellow to white solid
- Vapor Pressure: 0.00191mmHg at 25°C
- Melting Point: 50-59 °C
- Refractive Index: 1.54
- Boiling Point: 291.8 °C at 760 mmHg
- Flash Point: 127.3 °C
- PSA： 43.37000
- Density: 1.291 g/cm3
- LogP: 1.85220
Methyl 4-chlorocarbonylbenzoate(Cas 7377-26-6) Usage
InChI:InChI=1/C9H7ClO3/c1-13-9(12)7-4-2-6(3-5-7)8(10)11/h2-5H,1H3
7377-26-6 Relevant articles
Synthesis and fluorescence properties of environment-sensitive 7-(diethylamino)coumarin derivatives
Pajk, Stane
, p. 6044 - 6047 (2014)
By linking 7-(diethylamino)coumarin and ...
Exciplex Formation in Cholesteric Liquid Crystals Carrying Carbazolyl and Terephthaloyl Groups
Sisido, Masahiko,Wang, Xing-fang,Kawaguchi, Koji,Imanishi, Yukio
, p. 4801 - 4806 (1988)
Exciplex formation was observed in chole...
One-step Conversion of Amides and Esters to Acid Chlorides with PCl3
Li, Fangshao,Wu, Xiaofang,Guo, Fengzhe,Tang, Zi-Long,Xiao, Jing
supporting information, p. 4314 - 4317 (2021/07/16)
A general and efficient iodine-promoted ...
Method for preparing methyl 4-cyanobenzoate and method for preparing 4-cyanobenzoic acid
-
, (2021/06/09)
The invention relates to the field of sy...
sEH inhibitor and preparation method and application thereof
-
Paragraph 0225-0226, (2020/07/28)
The invention provides an sEH inhibitor ...
Palladium-Catalyzed Chlorocarbonylation of Aryl (Pseudo)Halides Through In Situ Generation of Carbon Monoxide
Bismuto, Alessandro,Boehm, Philip,Morandi, Bill,Roediger, Sven
supporting information, p. 17887 - 17896 (2020/08/19)
An efficient palladium-catalyzed chloroc...
7377-26-6 Process route
-
-
120-61-6
1,4-benzenedicarboxylic acid dimethyl ester
-
-
7377-26-6
4-Methoxycarbonylbenzoyl chloride
Conditions
| Conditions | Yield |
|---|---|
|
1,4-benzenedicarboxylic acid dimethyl ester;
With
potassium hydroxide;
In
methanol; toluene;
at 65 ℃;
for 3h;
With
thionyl chloride;
In
toluene;
at 67 ℃;
for 3h;
Inert atmosphere;
|
73%
|
|
With
iodine; phosphorus trichloride;
at 160 ℃;
for 48h;
Schlenk technique;
Sealed tube;
|
50%
|
|
Multistep reaction;
(i) KOH, MeOH, (ii) SOCl2, Py, benzene;
|
|
|
Multi-step reaction
with
2
steps
1: 73 percent / KOH / methanol; diethyl ether; H2
O / 21 h
2: 91 percent / thionyl chloride; pyridine / benzene / 5 h / Heating
With
pyridine; potassium hydroxide; thionyl chloride;
In
methanol; diethyl ether; water; benzene;
|
|
|
Multi-step reaction
with
2
steps
1: N2
H4
2: chlorine; HCl
With
hydrogenchloride; chlorine; hydrazine;
|
|
|
Multi-step reaction
with
2
steps
1: aq. KOH / methanol
2: SOCl2
With
potassium hydroxide; thionyl chloride;
In
methanol;
|
|
|
Multi-step reaction
with
2
steps
1.1: methanol / 0.5 h / 20 °C / Reflux; Inert atmosphere
1.2: Reflux; Inert atmosphere
2.1: thionyl chloride / 4 h / Reflux; Inert atmosphere
With
thionyl chloride;
In
methanol;
|
|
|
Multi-step reaction
with
2
steps
1: potassium hydroxide / methanol; toluene / 5.5 h / 45 - 50 °C
2: bis(trichloromethyl) carbonate / toluene; N,N-dimethyl-formamide / Reflux
With
bis(trichloromethyl) carbonate; potassium hydroxide;
In
methanol; N,N-dimethyl-formamide; toluene;
|
|
|
Multi-step reaction
with
2
steps
1: potassium hydroxide / toluene; methanol / 3.75 h / 65 °C
2: thionyl chloride / toluene / 3 h / 67 °C / Inert atmosphere
With
thionyl chloride; potassium hydroxide;
In
methanol; toluene;
|
|
|
Multi-step reaction
with
2
steps
1: potassium hydroxide / methanol; diethyl ether; water / 24 h / 20 °C
2: thionyl chloride; pyridine / 24 h / Reflux
With
pyridine; thionyl chloride; potassium hydroxide;
In
methanol; diethyl ether; water;
|
|
|
Multi-step reaction
with
2
steps
1: potassium hydroxide / methanol / 3.5 h / Reflux
2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 4 h / 0 - 20 °C
With
oxalyl dichloride; N,N-dimethyl-formamide; potassium hydroxide;
In
methanol; dichloromethane;
|
|
|
Multi-step reaction
with
2
steps
1: potassium hydroxide / methanol / Reflux
2: thionyl chloride / 2.5 h / Reflux
With
thionyl chloride; potassium hydroxide;
In
methanol;
|
|
|
Multi-step reaction
with
2
steps
1: potassium hydroxide; methanol / 4 h / 65 °C
2: N,N-dimethyl-formamide; thionyl chloride / toluene / 2 h / Reflux
With
methanol; thionyl chloride; N,N-dimethyl-formamide; potassium hydroxide;
In
toluene;
|
-
-
42967-55-5
monomethyl monopotassium terephthalate
-
-
7377-26-6
4-Methoxycarbonylbenzoyl chloride
Conditions
| Conditions | Yield |
|---|---|
|
With
thionyl chloride;
In
toluene;
at 67 ℃;
for 3h;
Inert atmosphere;
|
73%
|
|
With
thionyl chloride;
In
toluene;
|
|
|
With
bis(trichloromethyl) carbonate;
In
N,N-dimethyl-formamide; toluene;
Reflux;
|
7377-26-6 Upstream products
-
1679-64-7
Monomethyl terephthalate
-
13188-55-1
4-hydrazinocarbonylbenzoic acid methyl ester
-
67-56-1
methanol
-
100-20-9
terephthaloyl chloride
7377-26-6 Downstream products
-
22744-13-4
4-(2-diazoacetyl)benzoic acid methyl ester
-
20093-73-6
terephthalic acid-(2-acetyl-phenyl ester)-methyl ester
-
6724-91-0
N ,N '-hexanediyl-bis-terephthalamic acid dimethyl ester
-
5611-81-4
1,4-bis[2-[[4-(methoxycarbonyl) benzoyl]oxy]ethyl] 1,4-benzenedicarboxylate