What is the Trimethyl orthobenzoate?

Trimethyl orthobenzoate is clear colorless liquid, while it's Molecular Formula is C10H14O3. clear colorless liquid Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

What is the CAS number for Trimethyl orthobenzoate?

The CAS number of Trimethyl orthobenzoate is 707-07-3.

What is Trimethyl orthobenzoate (707-07-3) used for?

Trimethyl orthobenzoate is an organic compound that serves as a versatile reagent in various chemical reactions and pharmaceutical applications. It is characterized by its ability to participate in the synthesis of complex organic molecules, making it a valuable component in the development of new drugs and therapies.InChI:InChI=1/C10H20O3/c1-11-10(12-2,13-3)9-7-5-4-6-8-9/h9H,4-8H2,1-3H3

What is the Trimethyl orthobenzoate?

Trimethyl orthobenzoate is clear colorless liquid, while it's Molecular Formula is C10H14O3. clear colorless liquid Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

What is the CAS number for Trimethyl orthobenzoate?

The CAS number of Trimethyl orthobenzoate is 707-07-3.

What is Trimethyl orthobenzoate (707-07-3) used for?

Trimethyl orthobenzoate is an organic compound that serves as a versatile reagent in various chemical reactions and pharmaceutical applications. It is characterized by its ability to participate in the synthesis of complex organic molecules, making it a valuable component in the development of new drugs and therapies.InChI:InChI=1/C10H20O3/c1-11-10(12-2,13-3)9-7-5-4-6-8-9/h9H,4-8H2,1-3H3

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Trimethyl orthobenzoate

CAS
Purity

707-07-3
99%

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Factory supply good quality Trimethyl orthobenzoate 707-07-3 with stock

Molecular Formula: C10H14O3
Molecular Weight: 182.219
Appearance/Colour: clear colorless liquid
Vapor Pressure: 0.344mmHg at 25°C
Refractive Index: n20/D 1.489(lit.)
Boiling Point: 223.9 °C at 760 mmHg
Flash Point: 82.2 °C
PSA： 27.69000
Density: 1.04 g/cm³
LogP: 1.73610

Trimethyl orthobenzoate(Cas 707-07-3) Usage

Synthesis Reference(s)	Journal of the American Chemical Society, 72, p. 1661, 1950 DOI: 10.1021/ja01160a067
General Description	Trimethyl orthobenzoate reacts with P-dimethylaminophosphonic acid bis(1-methylhydrazide) to yield 1,2,5,6-tetrahydro-1,5-dimethyl-6-(N,N-dimethylamino)-6-phenyl-1,2,4,5,6-tetrazaphosphorine-6-oxide.

InChI:InChI=1/C10H20O3/c1-11-10(12-2,13-3)9-7-5-4-6-8-9/h9H,4-8H2,1-3H3

707-07-3 Relevant articles

Anodic oxidation of dithiane carboxylic acids: A rapid and mild way to access functionalized orthoesters

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A new electrochemical methodology has be...

Enantioselective Desymmetrization of cis-3,5- O-Arylidenecyclohexanones Catalyzed by Cinchona-Derived Quaternary Ammonium Salts

Cortigiani, Mauro,Gillick Healy, Malachi,Mereu, Andrea,Adamo, Mauro F. A.

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An enantioselective protocol for the des...

A flexible Pinner preparation of orthoesters: The model case of trimethylorthobenzoate

Noe, Marco,Perosa, Alvise,Selva, Maurizio

, p. 2252 - 2260 (2013/09/24)

In the absence of additional solvents, a...

ELECTROCHEMICAL CLEAVAGE OF THE DOUBLE BOND OF 1-ALKENYLARENES

Ogibin, Yu. N.,Sokolov, A. B.,Ilovaiskii, A. I.,Elison, M. N.,Nikishin, G. I.

, p. 561 - 566 (2007/10/02)

A study has been made of the electrochem...

707-07-3 Process route

: 67-56-1
methanol

: 87775-62-0
4-nitrophenyl N-phenylbenzimidate

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 62-53-3
aniline

: 707-07-3
orthobenzoic acid trimethyl ester

Conditions

Conditions	Yield
With hydrogenchloride; at 25 ℃; Product distribution; Rate constant; Mechanism;

: 100-47-0
benzonitrile

: 55-21-0,27208-38-4
benzamide

: 707-07-3
orthobenzoic acid trimethyl ester

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride / 10 h / 5 - 10 °C 2: 240 h / 20 °C With hydrogenchloride;
Multi-step reaction with 4 steps 1: hydrogenchloride / 10 h / 5 - 10 °C 2: potassium carbonate / ethyl acetate; water / 5 °C 3: phosphoric acid / ethyl acetate; methanol / 1 h / 5 °C 4: 4 h / 65 °C With hydrogenchloride; phosphoric acid; potassium carbonate; In methanol; water; ethyl acetate;