- CAS
- Purity
- 60719-84-8
- 99%
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High quality purity >99% Amrinone 60719-84-8 for sale We supply high quality Amrinone (CAS 60719-84-8), in stock, factory directly supply to clients, lower prices, more competitiveness.
Amrinone is Crystalline solid, while it's Molecular Formula is C10H9N3O. Amrinone is used for short-term treatment of cardiac insufficiency that does not respond to treatment of other drugs.
The CAS number of Amrinone is 60719-84-8.
More information of Amrinone 60719-84-8 are:
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Synonyms |
3-Amino-5-(4-pyridinyl)-2(1H)-pyridinone;Amrinone (TN);Prestwick_44;Wincoram;5-Amino-(3,4-bipyridin)-6(1H)-one;Cordemcura;(3,4-Bipyridin)-6(1h)-one, 5-amino-;Amrinona [INN-Spanish];5-25-15-00181 (Beilstein Handbook Reference);Amrinonum [INN-Latin];Amrinone [USAN:BAN:INN];Inamrinone;Inamrinone (USP);[3,4'-Bipyridin]-6(1H)-one,5-amino-;Inocor;3-amino-5-pyridin-4-yl-1H-pyridin-2-one;Amrinone (JAN);5-amino-3,4′-bipyridin-6(1H)-one;5-Amino-5-(4-pyridinyl)-2(1 h)-pyridinone; |
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CAS?Number |
60719-84-8 |
|
Molecular Formula |
C10H9N3O |
|
Molecular Weight |
187.201 |
|
Density |
1.277 g/cm3 |
|
Melting Point |
294-297 °C (dec.) |
|
Boiling Point |
451.5 °C at 760 mmHg |
|
Flash Point |
226.9 °C |
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HS CODE |
29333999 |
|
PSA |
71.77000 |
|
LogP |
1.60030 |
|
Pka |
12.05±0.10(Predicted) |
Amrinone is an inhibitor of phosphodiesterase 3 (PDE3; IC50 = 19.5 μM). It increases developed tension and contractile force in isolated cat papillary muscle. Amrinone (1-10 mg/kg) has positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.
InChI:InChI=1/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)
Articles related to Amrinone:
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Article |
Source |
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Synthesis of a stable pyridyl boronate and its reaction with aryl and heteroaryl halides |
Durrant, Steven J.,Pinder, Joanne L.,Charrier, Jean-Damien,Jimenez, Juan-Miguel,Brenchley, Guy,Collier, Philip N.,Kay, David,Miller, Andrew,Pierard, Francoise,Ramaya, Sharn,Sadiq, Shazia,Twin, Heather C. , p. 509 - 517 (2008/02/02) |
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N-Hydroxy-1,2-dihydro-2-oxo-5-(pyridinyl)-nicotinimidamide and their cardiotonic use |
- , (2008/06/13) |
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