- CAS
- Purity
- 2483-49-0
- 99%
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Used in Biochemical Research:
BOC-ALA-ONP is used as a substrate in biochemical research for studying enzymatic reactions. Its color change upon reaction allows for easy monitoring and quantification of enzyme activity.
Used in Pharmaceutical Synthesis:
BOC-ALA-ONP is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. The p-nitrophenyl group is a common component in the synthesis of various drugs, and the BOC-ALA-ONP compound can be a useful precursor in such processes.
Used in Analytical Chemistry:
BOC-ALA-ONP is used as a reagent in analytical chemistry for the detection and quantification of specific enzymes or other biomolecules. The color change associated with its reaction can be measured spectrophotometrically, providing a sensitive and reliable method for analysis.
Used in Educational Laboratories:
BOC-ALA-ONP is used as a teaching aid in educational laboratories to demonstrate the principles of enzymatic reactions and the use of colorimetric assays. Students can observe the color change and learn about the relationship between enzyme activity and reaction kinetics.
4-nitro-phenol
L-N-Boc-Ala
tert-butyloxycarbonyl-L-alanine p-nitrophenyl ester
| Conditions | Yield |
|---|---|
|
With
dicyclohexyl-carbodiimide;
In
dichloromethane;
|
85%
|
|
With
dicyclohexyl-carbodiimide;
In
dichloromethane;
at 20 ℃;
|
85%
|
|
With
dmap;
In
dichloromethane;
for 1h;
Ambient temperature;
|
78%
|
|
With
2,6-di-tert-butyl-4-methyl-phenol;
In
pyridine; benzene;
|
60%
|
|
With
dicyclohexyl-carbodiimide;
|
|
|
Multistep reaction;
(i) ClCO2iBu, Et3N, THF, (ii) /BRN= 1281877/;
|
|
|
With
dicyclohexyl-carbodiimide;
In
ethyl acetate;
|
|
|
With
dicyclohexyl-carbodiimide;
In
ethyl acetate;
Ambient temperature;
|
|
|
With
dmap; dicyclohexyl-carbodiimide;
In
ethyl acetate;
|
L-N-Boc-Ala
1-nitro-4-trifluoroacetoxy-benzene
tert-butyloxycarbonyl-L-alanine p-nitrophenyl ester
| Conditions | Yield |
|---|---|
|
With
pyridine;
|
The CAS number of BOC-ALA-ONP is 2483-49-0.
More information of BOC-ALA-ONP 2483-49-0 are:
|
CAS?Number |
2483-49-0 |
|
Density |
1.237 g/cm3 |
|
Melting Point |
78 °C(Solv: methanol (67-56-1)) |
|
Boiling Point |
460.9 °C at 760 mmHg |
|
Flash Point |
232.6 °C |
|
Vapor Pressure |
1.12E-08mmHg at 25°C |
|
Refractive Index |
1.528 |
|
PSA |
110.45000 |
|
LogP |
3.32750 |
|
Pka |
10.87±0.46(Predicted) |
Synonyms?for?BOC-ALA-ONP 2483-49-0:Alanine,N-carboxy-, N-tert-butyl p-nitrophenyl ester (7CI);Alanine, N-carboxy-,N-tert-butyl p-nitrophenyl ester, L- (8CI);BOC-L-Alanine p-nitrophenyl ester;N-(tert-Butyloxycarbonyl)-L-alanine p-nitrophenyl ester;N-tert-Butoxycarbonyl-L-alanine p-nitrophenyl ester;p-NitrophenylN-tert-butoxycarbonyl-L-alaninate;p-Nitrophenyl N-tert-butyloxycarbonyl-L-alaninate;p-Nitrophenyl tert-butoxycarbonyl-L-alaninate;tert-Butyloxycarbonyl-L-alaninep-nitrophenyl ester;Boc-Ala-ONP;
The chemical formula of ?BOC-ALA-ONP is?C14H18N2O6 which containing 14 Carbon atoms,18 Hydrogen atoms,2 Nitrogen atoms and 6 Oxygen atoms,and the molecular weight of??BOC-ALA-ONP?is 310.307.
BOC-ALA-ONP, or t-Butyloxycarbonyl-L-alanine-p-nitrophenyl ester, is a chemical compound utilized in biochemical research and analysis. It is composed of a protective group (BOC), a simple non-essential amino acid (ALA), and a p-nitrophenyl moiety (ONP). BOC-ALA-ONP is particularly useful in laboratory applications and experiments, especially those involving enzymatic reactions, due to its color-changing property upon reaction.
InChI:InChI=1/C14H18N2O6/c1-9(15-13(18)22-14(2,3)4)12(17)21-11-7-5-10(6-8-11)16(19)20/h5-9H,1-4H3,(H,15,18)/t9-/m0/s1
Relevant articles related to BOC-ALA-ONP:
|
Article |
Source |
|
A simple synthesis of imide-dipeptides |
Ke, Damei,Zhan, Chuanlang,Li, Xiao,Li, Alexander D. Q.,Yao, Jiannian experimental part, p. 1506 - 1510 (2009/12/24) |
|
Synthesis of glutamate receptor antagonist philanthotoxin-433 (PhTX-433) and its analogs |
Goodnow Jr.,Konno,Niwa,Kallimopoulos,Bukownik,Lenares,Nakanishi , p. 3267 - 3286 (2007/10/02) |
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